FOG17730
EOG84TMTD

sce:SEC72

Genes: 24

SGD Description
Non-essential subunit of Sec63 complex; with Sec61 complex, Kar2p/BiP and Lhs1p forms a channel competent for SRP-dependent and post-translational SRP-independent protein targeting and import into the ER; other members are Sec63p, Sec62p, and Sec66p


References

Deshaies RJ, et al. (1991 Feb 28). Assembly of yeast Sec proteins involved in translocation into the endoplasmic reticulum into a membrane-bound multisubunit complex.

Belhumeur P, et al. (1993 Apr). GSP1 and GSP2, genetic suppressors of the prp20-1 mutant in Saccharomyces cerevisiae: GTP-binding proteins involved in the maintenance of nuclear organization.

Brodsky JL, et al. (1993 Dec). A Sec63p-BiP complex from yeast is required for protein translocation in a reconstituted proteoliposome.

Bushman JL, et al. (1993 Mar). Evidence that GCD6 and GCD7, translational regulators of GCN4, are subunits of the guanine nucleotide exchange factor for eIF-2 in Saccharomyces cerevisiae.

Feldheim D, et al. (1994 Aug). Sec72p contributes to the selective recognition of signal peptides by the secretory polypeptide translocation complex.

Panzner S, et al. (1995 May 19). Posttranslational protein transport in yeast reconstituted with a purified complex of Sec proteins and Kar2p.

Willer M, et al. (2003 Jan 30). Identification of novel protein-protein interactions at the cytosolic surface of the Sec63 complex in the yeast ER membrane.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%