FOG17709
EOG84XH01

sce:CEG1

Genes: 34

SGD Description
Guanylyltransferase involved in mRNA 5' capping; subunit of the mRNA capping enzyme, which is a heterotetramer composed of two molecules of Ceg1p and a homodimer of Cet1p, the mRNA 5?-triphosphatase subunit; nuclear import of Ceg1p requires interaction with Cet1p; mammalian capping enzyme is a single bifunctional polypeptide


PomBase Description
mRNA guanylyltransferase Ceg1


AspGD Description
Ortholog(s) have mRNA guanylyltransferase activity, role in 7-methylguanosine mRNA capping and nucleus localization


References

Itoh N, et al. (1984 Nov 25). Messenger RNA guanlyltransferase from Saccharomyces cerevisiae. II. Catalytic properties.

Itoh N, et al. (1984 Nov 25). Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. I. Purification and subunit structure.

Itoh N, et al. (1987 Feb 15). Messenger RNA guanylyltransferase from Saccharomyces cerevisiae. Large scale purification, subunit functions, and subcellular localization.

Shibagaki Y, et al. (1992 May 15). mRNA capping enzyme. Isolation and characterization of the gene encoding mRNA guanylytransferase subunit from Saccharomyces cerevisiae.

Shuman S, et al. (1994 Dec 6). Covalent catalysis in nucleotidyl transfer reactions: essential motifs in Saccharomyces cerevisiae RNA capping enzyme are conserved in Schizosaccharomyces pombe and viral capping enzymes and among polynucleotide ligases.

Fresco LD, et al. (1994 Jul 5). Active site of the mRNA-capping enzyme guanylyltransferase from Saccharomyces cerevisiae: similarity to the nucleotidyl attachment motif of DNA and RNA ligases.

Yamagishi M, et al. (1995 Nov 15). Isolation of temperature-sensitive mutants for mRNA capping enzyme in Saccharomyces cerevisiae.

Pei Y, et al. (2001). RNA triphosphatase is essential in Schizosaccharomyces pombe and Candida albicans.

Pei Y, et al. (2001 Jul 27). The length, phosphorylation state, and primary structure of the RNA polymerase II carboxyl-terminal domain dictate interactions with mRNA capping enzymes.

Takagi T, et al. (2002 Jun). Divergent subunit interactions among fungal mRNA 5'-capping machineries.

Pei Y, et al. (2002 May 31). Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.

Schneider S, et al. (2010 May). Separable functions of the fission yeast Spt5 carboxyl-terminal domain (CTD) in capping enzyme binding and transcription elongation overlap with those of the RNA polymerase II CTD.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Doamekpor SK, et al. (2014 Jun 15). How an mRNA capping enzyme reads distinct RNA polymerase II and Spt5 CTD phosphorylation codes.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%