FOG17698
EOG84XH23

sce:SLP1

Genes: 31

SGD Description
Glycosylated integral ER membrane protein of unknown function; forms an ER-membrane associated protein complex with Emp65p; member of the SUN-like family of proteins; genetic interactions suggest a role in folding of ER membrane proteins; required for nuclear envelope localization of Mps3p


PomBase Description
Sad1-UNC-like protein involved protein folding in the ER (predicted)


AspGD Description
Ortholog(s) have role in protein folding in endoplasmic reticulum and integral component of endoplasmic reticulum membrane localization


References

Terashima H, et al. (2002 Feb). Sequence-based approach for identification of cell wall proteins in Saccharomyces cerevisiae.

Jaspersen SL, et al. (2006 Aug 28). The Sad1-UNC-84 homology domain in Mps3 interacts with Mps2 to connect the spindle pole body with the nuclear envelope.

Jonikas MC, et al. (2009 Mar 27). Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Friederichs JM, et al. (2012 Dec). Genetic analysis of Mps3 SUN domain mutants in Saccharomyces cerevisiae reveals an interaction with the SUN-like protein Slp1.

Zhang L, et al. (2013). Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
30 genes with posterior transmembrane prediction > 50%