FOG17668
EOG851C75

sce:GWT1

Genes: 34

SGD Description
Protein involved in the inositol acylation of GlcN-PI; the inositol acylation of glucosaminyl phosphatidylinositol (GlcN-PI) forms glucosaminyl(acyl)phosphatidylinositol (GlcN(acyl)PI), an intermediate in the biosynthesis of glycosylphosphatidylinositol (GPI) anchors


PomBase Description
pig-W


AspGD Description
Ortholog(s) have glucosaminyl-phosphotidylinositol O-acyltransferase activity and role in GPI anchor biosynthetic process, cellular response to drug


References

Umemura M, et al. (2003 Jun 27). GWT1 gene is required for inositol acylation of glycosylphosphatidylinositol anchors in yeast.

Tsukahara K, et al. (2003 May). Medicinal genetics approach towards identifying the molecular target of a novel inhibitor of fungal cell wall assembly.

Murakami Y, et al. (2003 Oct). PIG-W is critical for inositol acylation but not for flipping of glycosylphosphatidylinositol-anchor.

Martín-Castellanos C, et al. (2005 Nov 22). A large-scale screen in S. pombe identifies seven novel genes required for critical meiotic events.

Okamoto M, et al. (2006 Feb 17). Glycosylphosphatidylinositol-anchored proteins are required for the transport of detergent-resistant microdomain-associated membrane proteins Tat2p and Fur4p.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Amorim MJ, et al. (2010 Jun 8). Global coordination of transcriptional control and mRNA decay during cellular differentiation.

Kawashima SA, et al. (2012 Jul 27). Analyzing fission yeast multidrug resistance mechanisms to develop a genetically tractable model system for chemical biology.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 34 genes with posterior transmembrane prediction > 50%