FOG17643
EOG8547DJ

sce:VPS8

Genes: 33

SGD Description
Membrane-binding component of the CORVET complex; involved in endosomal vesicle tethering and fusion in the endosome to vacuole protein targeting pathway; interacts with Vps21p; contains RING finger motif


PomBase Description
WD repeat protein Vps8 (predicted)


AspGD Description
Ortholog(s) have GTPase binding, protein anchor activity and role in late endosome to vacuole transport via multivesicular body sorting pathway, protein targeting to vacuole


References

Clark MW, et al. (1994 Apr). Sequencing of chromosome I of Saccharomyces cerevisiae: analysis of the 42 kbp SPO7-CENI-CDC15 region.

Chen YJ, et al. (1996 Aug). The VPS8 gene is required for localization and trafficking of the CPY sorting receptor in Saccharomyces cerevisiae.

Galagan JE, et al. (2005 Dec 22). Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.

Abenza JF, et al. (2010 Aug 1). Aspergillus RabB Rab5 integrates acquisition of degradative identity with the long distance movement of early endosomes.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 18 genes with posterior transmembrane prediction > 50%