FOG17625
EOG8547J0

sce:SKI6

Genes: 34

SGD Description
Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; has similarity to E. coli RNase PH and to human hRrp41p (EXOSC4)


PomBase Description
exosomal 3'-to-5' phosphorolytic exoribonuclease Rrp41


AspGD Description
Ortholog(s) have role in U1 snRNA 3'-end processing, U4 snRNA 3'-end processing and U5 snRNA 3'-end processing, more


References

Mitchell P, et al. (1997 Nov 14). The exosome: a conserved eukaryotic RNA processing complex containing multiple 3'-->5' exoribonucleases.

Allmang C, et al. (1999 Aug 15). The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.

Taricani L, et al. (2002 Mar 22). The fission yeast ES2 homologue, Bis1, interacts with the Ish1 stress-responsive nuclear envelope protein.

Liu Q, et al. (2006 Dec 15). Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Dziembowski A, et al. (2007 Jan). A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Bonneau F, et al. (2009 Oct 30). The yeast exosome functions as a macromolecular cage to channel RNA substrates for degradation.

Malecki M, et al. (2013 Jul 3). The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%