FOG17519
EOG85DV76

sce:TAP42

Genes: 31

SGD Description
Essential protein involved in the TOR signaling pathway; physically associates with the protein phosphatase 2A and the SIT4 protein phosphatase catalytic subunits


PomBase Description
TAP42 family protein involved in TOR signalling Tap42 (predicted)


AspGD Description
Ortholog(s) have role in TOR signaling, positive regulation of transcription from RNA polymerase I promoter and cytosol, extrinsic component of membrane, nucleus localization


References

Di Como CJ, et al. (1996 Aug 1). Nutrients, via the Tor proteins, stimulate the association of Tap42 with type 2A phosphatases.

Jiang Y, et al. (1999 May 17). Tor proteins and protein phosphatase 2A reciprocally regulate Tap42 in controlling cell growth in yeast.

Jacinto E, et al. (2001 Nov). TIP41 interacts with TAP42 and negatively regulates the TOR signaling pathway.

Düvel K, et al. (2003 Jun). Multiple roles of Tap42 in mediating rapamycin-induced transcriptional changes in yeast.

Wang H, et al. (2003 May). The Tap42-protein phosphatase type 2A catalytic subunit complex is required for cell cycle-dependent distribution of actin in yeast.

Wang H, et al. (2003 Nov). Interaction with Tap42 is required for the essential function of Sit4 and type 2A phosphatases.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Santhanam A, et al. (2004 Oct). PP2A phosphatase activity is required for stress and Tor kinase regulation of yeast stress response factor Msn2p.

Fitzgibbon GJ, et al. (2005 Sep). Genetic analysis of the TOR pathway in Aspergillus nidulans.

Ikebe C, et al. (2011). Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%