FOG17381
EOG85TB4B

sce:TRM5

Genes: 34

SGD Description
tRNA(m(1)G37)methyltransferase; methylates a tRNA base adjacent to the anticodon that has a role in prevention of frameshifting; highly conserved across Archaea, Bacteria, and Eukarya


PomBase Description
tRNA (guanine) methyltransferase Trm5 (predicted)


AspGD Description
Ortholog(s) have role in regulation of DNA methylation and nucleus localization


References

Björk GR, et al. (2001 Jan 15). A primordial tRNA modification required for the evolution of life?

Lee C, et al. (2007 Sep 21). Yeast mitochondrial initiator tRNA is methylated at guanosine 37 by the Trm5-encoded tRNA (guanine-N1-)-methyltransferase.

Jackman JE, et al. (2008). The use of Saccharomyces cerevisiae proteomic libraries to identify RNA-modifying proteins.

Ohira T, et al. (2011 Jun 28). Retrograde nuclear import of tRNA precursors is required for modified base biogenesis in yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%