FOG17352
EOG85X6B3

sce:TTI1

Genes: 32

SGD Description
Subunit of the ASTRA complex, involved in chromatin remodeling; telomere length regulator involved in the stability or biogenesis of PIKKs such as TORC1; similar to S. pombe Tti1p; detected in highly purified mitochondria in high-throughput studies


PomBase Description
Tel Two Interacting protein 1


AspGD Description
Ortholog(s) have role in chromatin remodeling and ASTRA complex, mitochondrion localization


References

Hayashi T, et al. (2007 Dec). Rapamycin sensitivity of the Schizosaccharomyces pombe tor2 mutant and organization of two highly phosphorylated TOR complexes by specific and common subunits.

Shevchenko A, et al. (2008). Chromatin Central: towards the comparative proteome by accurate mapping of the yeast proteomic environment.

Takai H, et al. (2010 Sep 15). Tel2 structure and function in the Hsp90-dependent maturation of mTOR and ATR complexes.

Helmlinger D, et al. (2011 Jun 3). Tra1 has specific regulatory roles, rather than global functions, within the SAGA co-activator complex.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 14 genes with posterior transmembrane prediction > 50%