FOG17214
EOG866T67

sce:ZIM17

Genes: 30

SGD Description
Protein co-chaperone with a zinc finger motif; essential for protein import into mitochondria; may act with Pam18p to facilitate recognition and folding of imported proteins by Ssc1p (mtHSP70) in the mitochondrial matrix; required for the maintenance of Ssc1p solubility and assists in the functional interaction of Ssc1p with substrate proteins


PomBase Description
TIM23 translocase complex subunit Tim15 (predicted)


AspGD Description
Ortholog(s) have mitochondrion localization


References

Kellis M, et al. (2003 May 15). Sequencing and comparison of yeast species to identify genes and regulatory elements.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Burri L, et al. (2004 Nov 26). Zim17, a novel zinc finger protein essential for protein import into mitochondria.

Sanjuán Szklarz LK, et al. (2005 Aug 5). Inactivation of the mitochondrial heat shock protein zim17 leads to aggregation of matrix hsp70s followed by pleiotropic effects on morphology and protein biogenesis.

Yamamoto H, et al. (2005 Jan 17). Identification of a novel member of yeast mitochondrial Hsp70-associated motor and chaperone proteins that facilitates protein translocation across the inner membrane.

Sichting M, et al. (2005 Mar 9). Maintenance of structure and function of mitochondrial Hsp70 chaperones requires the chaperone Hep1.

Momose T, et al. (2007 Jul). Structural basis of functional cooperation of Tim15/Zim17 with yeast mitochondrial Hsp70.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%