FOG17144
EOG86DJNF

sce:SLD5

Genes: 33

SGD Description
Subunit of the GINS complex (Sld5p, Psf1p, Psf2p, Psf3p); complex is localized to DNA replication origins and implicated in assembly of the DNA replication machinery


PomBase Description
GINS complex subunit Sld5


AspGD Description
Ortholog(s) have role in DNA-dependent DNA replication, cellular protein localization, double-strand break repair via break-induced replication and GINS complex, cytosol, replication fork protection complex localization


References

Takayama Y, et al. (2003 May 1). GINS, a novel multiprotein complex required for chromosomal DNA replication in budding yeast.

Huang HK, et al. (2005 Oct). Suppressors of Bir1p (Survivin) identify roles for the chromosomal passenger protein Pic1p (INCENP) and the replication initiation factor Psf2p in chromosome segregation.

Yabuuchi H, et al. (2006 Oct 4). Ordered assembly of Sld3, GINS and Cdc45 is distinctly regulated by DDK and CDK for activation of replication origins.

Handa T, et al. (2012 Aug). DNA polymerization-independent functions of DNA polymerase epsilon in assembly and progression of the replisome in fission yeast.

Kanke M, et al. (2012 May 2). Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components.

Das J, et al. (2013 May 21). Cross-species protein interactome mapping reveals species-specific wiring of stress response pathways.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%