FOG16986
EOG86T1MS

sce:BUD13

Genes: 29

SGD Description
Subunit of the RES complex; RES complex is required for nuclear pre-mRNA retention and splicing; involved in bud-site selection; diploid mutants display a unipolar budding pattern instead of the wild-type bipolar pattern due to a specific defect in MATa1 pre-mRNA splicing which leads to haploid gene expression in diploids


PomBase Description
complexed with Cdc5 protein Cwf26


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN7184, A. fumigatus Af293 : Afu4g03160, A. oryzae RIB40 : AO090011000095, Aspergillus wentii : Aspwe1_0160101 and Aspergillus sydowii : Aspsy1_0158366


References

Zahner JE, et al. (1996 Apr). Genetic analysis of the bipolar pattern of bud site selection in the yeast Saccharomyces cerevisiae.

Ni L, et al. (2001 Jul). A genomic study of the bipolar bud site selection pattern in Saccharomyces cerevisiae.

Ohi MD, et al. (2002 Apr). Proteomics analysis reveals stable multiprotein complexes in both fission and budding yeasts containing Myb-related Cdc5p/Cef1p, novel pre-mRNA splicing factors, and snRNAs.

Vincent K, et al. (2003 Jul). Genetic interactions with CLF1 identify additional pre-mRNA splicing factors and a link between activators of yeast vesicular transport and splicing.

Dziembowski A, et al. (2004 Dec 8). Proteomic analysis identifies a new complex required for nuclear pre-mRNA retention and splicing.

Ren L, et al. (2011 Feb 28). Systematic two-hybrid and comparative proteomic analyses reveal novel yeast pre-mRNA splicing factors connected to Prp19.

Livesay SB, et al. (2013 Nov). Structural and functional characterization of the N terminus of Schizosaccharomyces pombe Cwf10.

Bayne EH, et al. (2014). A systematic genetic screen identifies new factors influencing centromeric heterochromatin integrity in fission yeast.

Kallgren SP, et al. (2014). The proper splicing of RNAi factors is critical for pericentric heterochromatin assembly in fission yeast.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%