FOG16901
EOG873N7D

sce:MIH1

Genes: 33

SGD Description
Protein tyrosine phosphatase involved in cell cycle control; regulates the phosphorylation state of Cdc28p; homolog of S. pombe cdc25


PomBase Description
M phase inducer tyrosine phosphatase Cdc25


AspGD Description
Putative phosphotyrosine phosphatase


References

Morris NR, et al. (1975 Dec). Mitotic mutants of Aspergillus nidulans.

Bergen LG, et al. (1983 Oct). Kinetics of the nuclear division cycle of Aspergillus nidulans.

Bergen LG, et al. (1984 Jul). S-phase, G2, and nuclear division mutants of Aspergillus nidulans.

Russell P, et al. (1989 Apr 21). Conservation of mitotic controls in fission and budding yeasts.

Osmani AH, et al. (1991). Role of the cell-cycle-regulated NIMA protein kinase during G2 and mitosis: evidence for two pathways of mitotic regulation.

Osmani AH, et al. (1991 Oct 18). Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans.

Murray AW, et al. (1991 Oct 24). Cell Biology. Never-in-mitosis in mitosis.

Morris NR, et al. (1992). Mitotic regulation in Aspergillus nidulans.

O'Connell MJ, et al. (1992 Jun). An extra copy of nimEcyclinB elevates pre-MPF levels and partially suppresses mutation of nimTcdc25 in Aspergillus nidulans.

Doonan JH, et al. (1992 Nov). Cell division in Aspergillus.

Lu KP, et al. (1993 May). Essential roles for calcium and calmodulin in G2/M progression in Aspergillus nidulans.

Xiang X, et al. (1994 Mar 15). Cytoplasmic dynein is involved in nuclear migration in Aspergillus nidulans.

Pu RT, et al. (1995 Mar 1). Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit.

James SW, et al. (1995 Nov). The Aspergillus nidulans bimE (blocked-in-mitosis) gene encodes multiple cell cycle functions involved in mitotic checkpoint control and mitosis.

Ye XS, et al. (1996 Jul 15). Two S-phase checkpoint systems, one involving the function of both BIME and Tyr15 phosphorylation of p34cdc2, inhibit NIMA and prevent premature mitosis.

Ye XS, et al. (1997 Jan 2). The G2/M DNA damage checkpoint inhibits mitosis through Tyr15 phosphorylation of p34cdc2 in Aspergillus nidulans.

Harris SD, et al. (1998 Mar). Regulation of septum formation in Aspergillus nidulans by a DNA damage checkpoint pathway.

Prigozhina NL, et al. (2001 Oct). Gamma-tubulin and the C-terminal motor domain kinesin-like protein, KLPA, function in the establishment of spindle bipolarity in Aspergillus nidulans.

Goldman GH, et al. (2002 Apr). The DNA damage response in filamentous fungi.

Osmani SA, et al. (2004 Apr). The early impact of genetics on our understanding of cell cycle regulation in Aspergillus nidulans.

Bachewich C, et al. (2005 Jan). The polo-like kinase PLKA is required for initiation and progression through mitosis in the filamentous fungus Aspergillus nidulans.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Kato Y, et al. (2007 Sep). PinA from Aspergillus nidulans binds to pS/pT-P motifs using the same Loop I and XP groove as mammalian Pin1.

Son S, et al. (2009 Apr). Analysis of all protein phosphatase genes in Aspergillus nidulans identifies a new mitotic regulator, fcp1.

Liu HL, et al. (2009 Jan). The three fungal transmembrane nuclear pore complex proteins of Aspergillus nidulans are dispensable in the presence of an intact An-Nup84-120 complex.

Govindaraghavan M, et al. (2014 Aug). The Set1/COMPASS histone H3 methyltransferase helps regulate mitosis with the CDK1 and NIMA mitotic kinases in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%