FOG16894
EOG873N8G

sce:ENV7

Genes: 30

SGD Description
Vacuolar membrane protein kinase; negatively regulates membrane fusion; associates with vacuolar membrane through palmitoylation of one or more cysteines in consensus sequence; vacuolar membrane association is essential to its kinase activity; mutant shows defect in CPY processing; ortholog of human serine/threonine kinase 16 (STK16)


PomBase Description
serine/threonine protein kinase Ppk13 (predicted)


AspGD Description
Ortholog(s) have role in ascospore formation, conidiophore development, conidium formation, regulation of vacuole fusion, non-autophagic and response to oxidative stress, more


References

Zhu H, et al. (2000 Nov). Analysis of yeast protein kinases using protein chips.

Bimbó A, et al. (2005 Apr). Systematic deletion analysis of fission yeast protein kinases.

Roth AF, et al. (2006 Jun 2). Global analysis of protein palmitoylation in yeast.

Ikebe C, et al. (2011). Systematic localization study on novel proteins encoded by meiotically up-regulated ORFs in fission yeast.

Ricarte F, et al. (2011). A genome-wide immunodetection screen in S. cerevisiae uncovers novel genes involved in lysosomal vacuole function and morphology.

De Souza CP, et al. (2013). Functional analysis of the Aspergillus nidulans kinome.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Graml V, et al. (2014 Oct 27). A genomic Multiprocess survey of machineries that control and link cell shape, microtubule organization, and cell-cycle progression.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%