FOG16764
EOG859ZXT
EOG87H455

sce:PTP2

Genes: 14

SGD Description
Nuclear phosphotyrosine-specific phosphatase involved in osmosensing; involved in the inactivation of mitogen-activated protein kinase (MAPK) during osmolarity sensing; dephosporylates Hog1p MAPK and regulates its localization; with Msg5p co-regulates the calcium signaling pathway


References

James P, et al. (1992 Dec 1). Multiple protein tyrosine phosphatase-encoding genes in the yeast Saccharomyces cerevisiae.

Ota IM, et al. (1992 Mar 15). A gene encoding a putative tyrosine phosphatase suppresses lethality of an N-end rule-dependent mutant.

Guan K, et al. (1992 May 15). Isolation and characterization of a second protein tyrosine phosphatase gene, PTP2, from Saccharomyces cerevisiae.

Jacoby T, et al. (1997 Jul 11). Two protein-tyrosine phosphatases inactivate the osmotic stress response pathway in yeast by targeting the mitogen-activated protein kinase, Hog1.

Wurgler-Murphy SM, et al. (1997 Mar). Regulation of the Saccharomyces cerevisiae HOG1 mitogen-activated protein kinase by the PTP2 and PTP3 protein tyrosine phosphatases.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%