FOG16642
EOG87SQZK

sce:PHO80

Genes: 31

SGD Description
Cyclin; interacts with cyclin-dependent kinase Pho85p; regulates the response to nutrient levels and environmental conditions, including the response to phosphate limitation and stress-dependent calcium signaling


AspGD Description
Ortholog(s) have cyclin-dependent protein serine/threonine kinase regulator activity


References

Toh-e A, et al. (1986 Jun). Cloning and sequencing of the PHO80 gene and CEN15 of Saccharomyces cerevisiae.

Gilliquet V, et al. (1987 Jul 24). Sequence of the region 5' to the negative regulatory gene PHO80 of Saccharomyces cerevisiae.

Madden SL, et al. (1988 Mar 25). Structure and expression of the PHO80 gene of Saccharomyces cerevisiae.

Gilliquet V, et al. (1990 Dec 15). Negative regulatory elements of the Saccharomyces cerevisiae PHO system: interaction between PHO80 and PHO85 proteins.

Kaffman A, et al. (1994 Feb 25). Phosphorylation of the transcription factor PHO4 by a cyclin-CDK complex, PHO80-PHO85.

Jayaraman PS, et al. (1994 May 1). The activation domain of a basic helix-loop-helix protein is masked by repressor interaction with domains distinct from that required for transcription regulation.

Hirst K, et al. (1994 Nov 15). The transcription factor, the Cdk, its cyclin and their regulator: directing the transcriptional response to a nutritional signal.

Schneider KR, et al. (1994 Oct 7). Phosphate-regulated inactivation of the kinase PHO80-PHO85 by the CDK inhibitor PHO81.

O'Neill EM, et al. (1996 Jan 12). Regulation of PHO4 nuclear localization by the PHO80-PHO85 cyclin-CDK complex.

Kaffman A, et al. (1998 Dec 3). The receptor Msn5 exports the phosphorylated transcription factor Pho4 out of the nucleus.

Kaffman A, et al. (1998 Sep 1). Phosphorylation regulates association of the transcription factor Pho4 with its import receptor Pse1/Kap121.

Waters NC, et al. (2004 Jul). The yeast Pho80-Pho85 cyclin-CDK complex has multiple substrates.

Wu D, et al. (2004 Sep 3). The Pho80-like cyclin of Aspergillus nidulans regulates development independently of its role in phosphate acquisition.

Wanke V, et al. (2005 Dec 21). Regulation of G0 entry by the Pho80-Pho85 cyclin-CDK complex.

Sopko R, et al. (2006 Feb 3). Mapping pathways and phenotypes by systematic gene overexpression.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%