FOG16574
EOG880GG6

sce:GET4

Genes: 33

SGD Description
Protein involved in inserting tail-anchored proteins into ER membranes; forms a complex with Mdy2p; highly conserved across species and homologous to human gene C7orf20


PomBase Description
ER membrane insertion protein Get4 (predicted)


AspGD Description
Ortholog(s) have role in posttranslational protein targeting to membrane, protein insertion into ER membrane and TRC complex, nucleus localization


References

Jonikas MC, et al. (2009 Mar 27). Comprehensive characterization of genes required for protein folding in the endoplasmic reticulum.

Chang YW, et al. (2010 Mar 26). Crystal structure of Get4-Get5 complex and its interactions with Sgt2, Get3, and Ydj1.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%