FOG16491
EOG889331

sce:HSP60

Genes: 34

SGD Description
Tetradecameric mitochondrial chaperonin; required for ATP-dependent folding of precursor polypeptides and complex assembly; prevents aggregation and mediates protein refolding after heat shock; role in mtDNA transmission; phosphorylated


PomBase Description
mitochondrial heat shock protein Hsp60/Mcp60


AspGD Description
Mitochondrial heat shock protein


References

Johnson RB, et al. (1989 Dec 14). Cloning and characterization of the yeast chaperonin HSP60 gene.

Reading DS, et al. (1989 Feb 16). Characterization of the yeast HSP60 gene coding for a mitochondrial assembly factor.

Smiley JK, et al. (1992 Sep 25). The 66 kDa component of yeast SFI, stimulatory factor I, is hsp60.

Yoshida H, et al. (1995 Dec 29). Cloning and characterization of the mitochondrial HSP60-encoding gene of Schizosaccharomyces pombe.

Grandier-Vazeille X, et al. (2001 Aug 21). Yeast mitochondrial dehydrogenases are associated in a supramolecular complex.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Reinders J, et al. (2007 Nov). Profiling phosphoproteins of yeast mitochondria reveals a role of phosphorylation in assembly of the ATP synthase.

Kim Y, et al. (2007 Sep). Proteome map of Aspergillus nidulans during osmoadaptation.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Beltrao P, et al. (2009 Jun 16). Evolution of phosphoregulation: comparison of phosphorylation patterns across yeast species.

Oh YT, et al. (2010 Mar). Proteomic analysis of early phase of conidia germination in Aspergillus nidulans.

Snaith HA, et al. (2011 Jul 1). Characterization of Mug33 reveals complementary roles for actin cable-dependent transport and exocyst regulators in fission yeast exocytosis.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Sun W, et al. (2012 Feb). Targeting mitochondrial transcription in fission yeast with ETB, an inhibitor of HSP60, the chaperone that binds to the mitochondrial transcription factor Mtf1.

Di Y, et al. (2012 Feb 1). H₂O₂ stress-specific regulation of S. pombe MAPK Sty1 by mitochondrial protein phosphatase Ptc4.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Bernal M, et al. (2014 Jun). Proteome-wide search for PP2A substrates in fission yeast.

Vanoosthuyse V, et al. (2014 Jun). CPF-associated phosphatase activity opposes condensin-mediated chromosome condensation.

Chen W, et al. (2014 Mar). Endogenous U2·U5·U6 snRNA complexes in S. pombe are intron lariat spliceosomes.

Beckley JR, et al. (2015 Dec). A Degenerate Cohort of Yeast Membrane Trafficking DUBs Mediates Cell Polarity and Survival.

Jaimes-Arroyo R, et al. (2015 May). The SrkA Kinase Is Part of the SakA Mitogen-Activated Protein Kinase Interactome and Regulates Stress Responses and Development in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%