FOG16401
EOG88GTKJ

sce:TUB1;TUB3

Genes: 43

SGD Description
Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; relative distribution to nuclear foci increases upon DNA replication stress; TUB1 has a paralog, TUB3, that arose from the whole genome duplication|Alpha-tubulin; associates with beta-tubulin (Tub2p) to form tubulin dimer, which polymerizes to form microtubules; expressed at lower level than Tub1p; TUB3 has a paralog, TUB1, that arose from the whole genome duplication


PomBase Description
tubulin alpha 1|tubulin alpha 2


AspGD Description
Ortholog(s) have structural constituent of cytoskeleton activity|Ortholog(s) have role in ascospore formation, meiotic nuclear division


References

Sheir-Neiss G, et al. (1976 Mar 22). Tubulin-like protein from Aspergillus nidulans.

Davidse LC, et al. (1977 Jan). Differential binding of methyl benzimidazol-2-yl carbamate to fungal tubulin as a mechanism of resistance to this antimitotic agent in mutant strains of Aspergillus nidulans.

Morris NR, et al. (1979 Feb). Identification of a gene for alpha-tubulin in Aspergillus nidulans.

Oakley BR, et al. (1981 Jun). A beta-tubulin mutation in Aspergillus nidulans that blocks microtubule function without blocking assembly.

Gambino J, et al. (1984 Sep). Effects of mitotic and tubulin mutations on microtubule architecture in actively growing protoplasts of Aspergillus nidulans.

Morris NR, et al. (1986). Genetic and functional analysis of beta tubulin in Aspergillus nidulans.

Schatz PJ, et al. (1986 Nov). Two functional alpha-tubulin genes of the yeast Saccharomyces cerevisiae encode divergent proteins.

Oakley BR, et al. (1987 Jun). Conditionally lethal tubA alpha-tubulin mutations in Aspergillus nidulans.

Gualandi G, et al. (1987 May). Use of alpha- and beta-tubulin mutants for the study of spontaneous and induced chromosomal mis-distribution in Aspergillus nidulans.

Takahashi M, et al. (1989 Dec). Rhizoxin resistant mutants with an altered beta-tubulin gene in Aspergillus nidulans.

Doshi P, et al. (1991 Jan). Two alpha-tubulin genes of Aspergillus nidulans encode divergent proteins.

Bun-Ya M, et al. (1991 Jun). The PHO84 gene of Saccharomyces cerevisiae encodes an inorganic phosphate transporter.

Kirk KE, et al. (1991 Nov). The tubB alpha-tubulin gene is essential for sexual development in Aspergillus nidulans.

Lloyd AT, et al. (1991 Nov). Codon usage in Aspergillus nidulans.

Morris NR, et al. (1992 Jan). Mitotic gold in a mold: Aspergillus genetics and the biology of mitosis.

Doonan JH, et al. (1992 Nov). Cell division in Aspergillus.

Kirk KE, et al. (1993 Aug). Either alpha-tubulin isogene product is sufficient for microtubule function during all stages of growth and differentiation in Aspergillus nidulans.

Willins DA, et al. (1995 Dec). An alpha tubulin mutation suppresses nuclear migration mutations in Aspergillus nidulans.

Lee DW, et al. (1996 Apr 15). Quantitative analysis of gene expression in sexual structures of Aspergillus nidulans by sequencing of 3'-directed cDNA clones.

Clutterbuck AJ, et al. (1997 Jun). The validity of the Aspergillus nidulans linkage map.

Willins DA, et al. (1997 Jun). Mutations in the heavy chain of cytoplasmic dynein suppress the nudF nuclear migration mutation of Aspergillus nidulans.

Fischer R, et al. (1999 Jan). Nuclear movement in filamentous fungi.

Farkasovsky M, et al. (2001 Jan 22). Cortical Num1p interacts with the dynein intermediate chain Pac11p and cytoplasmic microtubules in budding yeast.

Requena N, et al. (2001 Oct). Genetic evidence for a microtubule-destabilizing effect of conventional kinesin and analysis of its consequences for the control of nuclear distribution in Aspergillus nidulans.

Oakley BR, et al. (2004 Apr). Tubulins in Aspergillus nidulans.

Su W, et al. (2004 Apr). Dual-Color imaging of nuclear division and mitotic spindle elongation in live cells of Aspergillus nidulans.

Xiang X, et al. (2004 Apr). Nuclear migration and positioning in filamentous fungi.

Efimov VP, et al. (2006 Apr). CLIP-170 homologue and NUDE play overlapping roles in NUDF localization in Aspergillus nidulans.

Mogensen J, et al. (2006 Aug). Transcription analysis using high-density micro-arrays of Aspergillus nidulans wild-type and creA mutant during growth on glucose or ethanol.

Savoldi M, et al. (2008 Oct). Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase.

Liu HL, et al. (2009 Jan). The three fungal transmembrane nuclear pore complex proteins of Aspergillus nidulans are dispensable in the presence of an intact An-Nup84-120 complex.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Szewczyk E, et al. (2011 Oct). Microtubule dynamics in mitosis in Aspergillus nidulans.

Seidel C, et al. (2012). The Aspergillus nidulans kinesin-3 tail is necessary and sufficient to recognize modified microtubules.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Gerke J, et al. (2012 Jun). Fungal S-adenosylmethionine synthetase and the control of development and secondary metabolism in Aspergillus nidulans.

Krohn NG, et al. (2014 Jan 10). The Aspergillus nidulans ATM kinase regulates mitochondrial function, glucose uptake and the carbon starvation response.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%