FOG16362
EOG88KPS7

sce:CFT2

Genes: 33

SGD Description
Subunit of the mRNA cleavage and polyadenlylation factor (CPF); required for pre-mRNA cleavage, polyadenylation and poly(A) site recognition, 43% similarity with the mammalian CPSF-100 protein.


PomBase Description
cleavage factor two Cft2/polyadenylation factor CPSF-73 (predicted)


AspGD Description
Ortholog(s) have mRNA cleavage and polyadenylation specificity factor complex localization


References

Zhao J, et al. (1997 Apr 18). Cleavage factor II of Saccharomyces cerevisiae contains homologues to subunits of the mammalian Cleavage/ polyadenylation specificity factor and exhibits sequence-specific, ATP-dependent interaction with precursor RNA.

Dichtl B, et al. (2001 Jun 15). Recognition of polyadenylation sites in yeast pre-mRNAs by cleavage and polyadenylation factor.

Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Kyburz A, et al. (2003 Jul 15). The role of the yeast cleavage and polyadenylation factor subunit Ydh1p/Cft2p in pre-mRNA 3'-end formation.

Mandel CR, et al. (2006 Dec 14). Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonuclease.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%