FOG16306
EOG88PK4M
sce:SSU72
Genes: 33
SGD DescriptionPhosphatase and transcription/RNA-processing factor; associates with TFIIB and cleavage/polyadenylation factor Pta1p; exhibits phosphatase activity on serine-5 and serine-7 of the RNA polymerase II C-terminal domain; affects start site selection and transcriptional read through in vivo
PomBase Descriptionphosphoric ester hydrolase Ssu72 (predicted)
AspGD DescriptionOrtholog(s) have CTD phosphatase activity, protein tyrosine phosphatase activity
References
Sun ZW, et al. (1996 Apr). Synthetic enhancement of a TFIIB defect by a mutation in SSU72, an essential yeast gene encoding a novel protein that affects transcription start site selection in vivo.
Ganem C, et al. (2003 Apr 1). Ssu72 is a phosphatase essential for transcription termination of snoRNAs and specific mRNAs in yeast.
Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.
Krishnamurthy S, et al. (2004 May 7). Ssu72 Is an RNA polymerase II CTD phosphatase.