FOG16274
EOG88SFBX

sce:DPH5

Genes: 33

SGD Description
Methyltransferase required for synthesis of diphthamide; diphthamide is a modified histidine residue of translation elongation factor 2 (Eft1p or Eft2p); not essential for viability; GFP-Dph5p fusion protein localizes to the cytoplasm


PomBase Description
diphthine synthase Dph5 (predicted)


AspGD Description
Diphthine synthase


References

Mattheakis LC, et al. (1992 Sep). DPH5, a methyltransferase gene required for diphthamide biosynthesis in Saccharomyces cerevisiae.

Nakai M, et al. (1993 Sep 23). Cloning of the YAP19 gene encoding a putative yeast homolog of AP19, the mammalian small chain of the clathrin-assembly proteins.

Lin Z, et al. (2014 Apr 30). Dph7 catalyzes a previously unknown demethylation step in diphthamide biosynthesis.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Malecki M, et al. (2016 Nov 25). Functional and regulatory profiling of energy metabolism in fission yeast.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%