FOG16163
EOG89321C

sce:NUP85

Genes: 27

SGD Description
Subunit of the Nup84p subcomplex of the nuclear pore complex (NPC); contributes to nucleocytoplasmic transport and NPC biogenesis and is involved in establishment of a normal nucleocytoplasmic concentration gradient of the GTPase Gsp1p; also plays roles in several processes that may require localization of genes or chromosomes at the nuclear periphery, including double-strand break repair, transcription and chromatin silencing; homologous to human NUP85 aka NUP75


PomBase Description
nucleoporin Nup85


References

Siniossoglou S, et al. (1996 Jan 26). A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.

Goldstein AL, et al. (1996 Jun). Pleiotropic nuclear defects associated with a conditional allele of the novel nucleoporin Rat9p/Nup85p.

Santos-Rosa H, et al. (1998 Nov). Nuclear mRNA export requires complex formation between Mex67p and Mtr2p at the nuclear pores.

Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Stage-Zimmermann T, et al. (2000 Nov). Factors affecting nuclear export of the 60S ribosomal subunit in vivo.

Allen NP, et al. (2002 Dec). Deciphering networks of protein interactions at the nuclear pore complex.

Lutzmann M, et al. (2002 Feb 1). Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

Gao H, et al. (2003 Jul 11). Nuclear accumulation of the small GTPase Gsp1p depends on nucleoporins Nup133p, Rat2p/Nup120p, Nup85p, Nic96p, and the acetyl-CoA carboxylase Acc1p.

Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 10 genes with posterior transmembrane prediction > 50%