FOG16004
EOG89GJ1F

sce:DPM1

Genes: 33

SGD Description
Dolichol phosphate mannose (Dol-P-Man) synthase of the ER membrane; catalyzes the formation of Dol-P-Man from Dol-P and GDP-Man; required for glycosyl phosphatidylinositol membrane anchoring, O mannosylation, and protein glycosylation


PomBase Description
dolichol-phosphate mannosyltransferase catalytic subunit Dpm1


AspGD Description
ER dolichyl-phosphate beta-d-mannosyltransferase; expression enhanced by maltose; induced by caspofungin


References

Orlean P, et al. (1988 Nov 25). Cloning and sequencing of the yeast gene for dolichol phosphate mannose synthase, an essential protein.

Colussi PA, et al. (1997 Jul 22). Human and Saccharomyces cerevisiae dolichol phosphate mannose synthases represent two classes of the enzyme, but both function in Schizosaccharomyces pombe.

Maeda Y, et al. (2000 Jun 1). Human dolichol-phosphate-mannose synthase consists of three subunits, DPM1, DPM2 and DPM3.

Kruszewska JS, et al. (2000 Oct). Dolichol phosphate mannose synthase from the filamentous fungus Trichoderma reesei belongs to the human and Schizosaccharomyces pombe class of the enzyme.

Banerjee DK, et al. (2005 Feb 11). In vitro phosphorylation by cAMP-dependent protein kinase up-regulates recombinant Saccharomyces cerevisiae mannosylphosphodolichol synthase.

Faulhammer F, et al. (2005 Jan 17). Cell growth-dependent coordination of lipid signaling and glycosylation is mediated by interactions between Sac1p and Dpm1p.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Lee J, et al. (2017 Feb 20). Chromatin remodeller Fun30^Fft3 induces nucleosome disassembly to facilitate RNA polymerase II elongation.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 13 genes with posterior transmembrane prediction > 50%