FOG15942
EOG83R22J
EOG89P8DC

sce:SIP3;YSP1

Genes: 32

SGD Description
Transcription cofactor; acts through interaction with DNA-bound Snf1p; C-terminal region has a putative leucine zipper motif; potential Cdc28p substrate; SIP3 has a paralog, YSP1, that arose from the whole genome duplication|Mitochondrial protein; potential role in promoting mitochondrial fragmentation during programmed cell death in response to high levels of alpha-factor mating pheromone or the drug amiodarone; YSP1 has a paralog, SIP3, that arose from the whole genome duplication


PomBase Description
pleckstrin homology domain protein


AspGD Description
Ortholog(s) have role in cellular response to drug


References

Lesage P, et al. (1994 Feb 25). Analysis of the SIP3 protein identified in a two-hybrid screen for interaction with the SNF1 protein kinase.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Gatta AT, et al. (2015 May 22). A new family of StART domain proteins at membrane contact sites has a role in ER-PM sterol transport.

Guydosh NR, et al. (2017 Sep 25). Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in <i>S. pombe</i>.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 31 genes with posterior transmembrane prediction > 50%