FOG15747
EOG8B5MN5

sce:HEL1

Genes: 33

SGD Description
RING finger ubiquitin ligase (E3); involved in ubiquitylation and degradation of excess histones; interacts with Ubc4p and Rad53p; null mutant sensitive to hydroxyurea (HU)


PomBase Description
ubiquitin-protein ligase E3 involved in sporulation Dbl4


AspGD Description
Ortholog(s) have cytosol, nucleus, site of double-strand break localization


References

Mata J, et al. (2002 Sep). The transcriptional program of meiosis and sporulation in fission yeast.

Rumpf C, et al. (2010 May). High-throughput knockout screen in Schizosaccharomyces pombe identifies a novel gene required for efficient homolog disjunction during meiosis I.

Singh RK, et al. (2012). Novel E3 ubiquitin ligases that regulate histone protein levels in the budding yeast Saccharomyces cerevisiae.

Yu Y, et al. (2013 Jun 1). A proteome-wide visual screen identifies fission yeast proteins localizing to DNA double-strand breaks.

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%