FOG15502
EOG8B5MQR
EOG8BRV4N

sce:RAP1

Genes: 25

SGD Description
Essential DNA-binding transcription regulator that binds many loci; involved in transcription activation and repression, chromatin silencing, and telomere length maintenance; relocalizes to the cytosol in response to hypoxia; conserved protein with an N-terminal BRCT domain, a central region with homology to the Myb DNA binding domain, and a C-terminal Rap1-specific protein-interaction domain (RCT domain)


References

Guiard B, et al. (1976). Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase).

Shore D, et al. (1987 Dec 4). Purification and cloning of a DNA binding protein from yeast that binds to both silencer and activator elements.

Tornow J, et al. (1993 Jun). GCR1, a transcriptional activator in Saccharomyces cerevisiae, complexes with RAP1 and can function without its DNA binding domain.

Giraldo R, et al. (1994 May 15). The yeast telomere-binding protein RAP1 binds to and promotes the formation of DNA quadruplexes in telomeric DNA.

Konig P, et al. (1996 Apr 5). The crystal structure of the DNA-binding domain of yeast RAP1 in complex with telomeric DNA.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%