FOG15482
EOG8BVQ94

sce:GRC3

Genes: 32

SGD Description
Polynucleotide kinase present on rDNA; required for efficient transcription termination by RNA polymerase I; functions with Las1p in a conserved mechanism to modulate rRNA processing and ribosome biogenesis; required for cell growth; mRNA is cell-cycle regulated


PomBase Description
polynucleotide kinase Grc3 (predicted)


AspGD Description
Ortholog(s) have role in chromatin silencing at centromere, cleavage in ITS2 between 5.8S rRNA and LSU-rRNA of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)


References

Ding DQ, et al. (2000 Mar). Large-scale screening of intracellular protein localization in living fission yeast cells by the use of a GFP-fusion genomic DNA library.

Peng WT, et al. (2003 Jun 27). A panoramic view of yeast noncoding RNA processing.

Braglia P, et al. (2010 Oct). Role of the RNA/DNA kinase Grc3 in transcription termination by RNA polymerase I.

Kitano E, et al. (2011 Apr 29). Roles of fission yeast Grc3 protein in ribosomal RNA processing and heterochromatic gene silencing.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Nie M, et al. (2015 Sep 25). High Confidence Fission Yeast SUMO Conjugates Identified by Tandem Denaturing Affinity Purification.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 2 genes with posterior transmembrane prediction > 50%