FOG15443
EOG8BZKJB

sce:ORC5

Genes: 30

SGD Description
Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing


PomBase Description
origin recognition complex subunit Orc5


AspGD Description
Ortholog(s) have DNA replication origin binding activity and nuclear chromatin, nuclear origin of replication recognition complex localization


References

Loo S, et al. (1995 Jun). The origin recognition complex in silencing, cell cycle progression, and DNA replication.

Chen S, et al. (2007 Nov 15). Orc6 is required for dynamic recruitment of Cdt1 during repeated Mcm2-7 loading.

Mimura S, et al. (2010 Mar 26). Cul8/Rtt101 forms a variety of protein complexes that regulate DNA damage response and transcriptional silencing.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 7 genes with posterior transmembrane prediction > 50%