FOG15364
EOG8C5B22

sce:PEP8

Genes: 34

SGD Description
Vacuolar protein component of the retromer; forms part of the multimeric membrane-associated retromer complex involved in vacuolar protein sorting along with Vps35p, Vps29p, Vps17p, and Vps5p; essential for endosome-to-Golgi retrograde protein transport; interacts with Ypt7p; protein abundance increases in response to DNA replication stress


PomBase Description
retromer complex subunit Vps26


AspGD Description
Ortholog(s) have role in cellular response to biotic stimulus, cellular response to starvation and filamentous growth of a population of unicellular organisms in response to biotic stimulus, more


References

Bachhawat AK, et al. (1994 Jun 15). The yeast homolog of H < beta > 58, a mouse gene essential for embryogenesis, performs a role in the delivery of proteins to the vacuole.

Seaman MN, et al. (1998 Aug 10). A membrane coat complex essential for endosome-to-Golgi retrograde transport in yeast.

Iwaki T, et al. (2006 May). Vacuolar protein sorting receptor in Schizosaccharomyces pombe.

Han TX, et al. (2010). Global fitness profiling of fission yeast deletion strains by barcode sequencing.

Pan X, et al. (2012 Nov 23). Identification of novel genes involved in DNA damage response by screening a genome-wide Schizosaccharomyces pombe deletion library.

Zhang L, et al. (2013). Genome-wide screening for genes associated with valproic acid sensitivity in fission yeast.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mojardín L, et al. (2015). Chromosome segregation and organization are targets of 5'-Fluorouracil in eukaryotic cells.

Hu L, et al. (2016 Aug). Genetic evidence for involvement of membrane trafficking in the action of 5-fluorouracil.

Burr R, et al. (2016 Jun 3). Mga2 Transcription Factor Regulates an Oxygen-responsive Lipid Homeostasis Pathway in Fission Yeast.

Guo L, et al. (2016 Oct 13). Global Fitness Profiling Identifies Arsenic and Cadmium Tolerance Mechanisms in Fission Yeast.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
2 genes with posterior transmembrane prediction > 50%