FOG15327
EOG8C867W

sce:NGG1

Genes: 33

SGD Description
Subunit of chromatin modifying histone acetyltransferase complexes; member of the ADA complex, the SAGA complex, and the SLIK complex; transcriptional regulator involved in glucose repression of Gal4p-regulated genes


PomBase Description
SAGA complex subunit Ngg1


AspGD Description
Ortholog(s) have histone acetyltransferase activity and role in histone acetylation, regulation of transcription from RNA polymerase II promoter


References

Brandl CJ, et al. (1993 Dec 15). Characterization of NGG1, a novel yeast gene required for glucose repression of GAL4p-regulated transcription.

Piña B, et al. (1993 Oct). ADA3: a gene, identified by resistance to GAL4-VP16, with properties similar to and different from those of ADA2.

Horiuchi J, et al. (1997 Jun). ADA1, a novel component of the ADA/GCN5 complex, has broader effects than GCN5, ADA2, or ADA3.

Grant PA, et al. (1998 Dec). The ATM-related cofactor Tra1 is a component of the purified SAGA complex.

Grant PA, et al. (1998 Jul 10). A subset of TAF(II)s are integral components of the SAGA complex required for nucleosome acetylation and transcriptional stimulation.

Grant PA, et al. (1999 Feb 26). Expanded lysine acetylation specificity of Gcn5 in native complexes.

Eberharter A, et al. (1999 Oct). The ADA complex is a distinct histone acetyltransferase complex in Saccharomyces cerevisiae.

Pray-Grant MG, et al. (2002 Dec). The novel SLIK histone acetyltransferase complex functions in the yeast retrograde response pathway.

Sterner DE, et al. (2002 Sep 3). SALSA, a variant of yeast SAGA, contains truncated Spt7, which correlates with activated transcription.

Wu PY, et al. (2004 Jul 23). Molecular architecture of the S. cerevisiae SAGA complex.

Pray-Grant MG, et al. (2005 Jan 27). Chd1 chromodomain links histone H3 methylation with SAGA- and SLIK-dependent acetylation.

Georgakopoulos P, et al. (2013). The Spt-Ada-Gcn5 Acetyltransferase (SAGA) complex in Aspergillus nidulans.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%