FOG15239
EOG8CFXQH

sce:VPS53

Genes: 33

SGD Description
Component of the GARP (Golgi-associated retrograde protein) complex; GARP is required for the recycling of proteins from endosomes to the late Golgi, and for mitosis after DNA damage induced checkpoint arrest; required for vacuolar protein sorting; members of the GARP complex are Vps51p-Vps52p-Vps53p-Vps54p,


PomBase Description
GARP complex subunit Vps53 (predicted)


AspGD Description
Ortholog(s) have cytoplasm localization


References

Conibear E, et al. (2000 Jan). Vps52p, Vps53p, and Vps54p form a novel multisubunit complex required for protein sorting at the yeast late Golgi.

Siniossoglou S, et al. (2001 Nov 1). An effector of Ypt6p binds the SNARE Tlg1p and mediates selective fusion of vesicles with late Golgi membranes.

Siniossoglou S, et al. (2002 Dec 13). Vps51p links the VFT complex to the SNARE Tlg1p.

Conibear E, et al. (2003 Apr). Vps51p mediates the association of the GARP (Vps52/53/54) complex with the late Golgi t-SNARE Tlg1p.

Reggiori F, et al. (2003 Feb 14). Vps51 is part of the yeast Vps fifty-three tethering complex essential for retrograde traffic from the early endosome and Cvt vesicle completion.

Panic B, et al. (2003 Mar 4). The ARF-like GTPases Arl1p and Arl3p act in a pathway that interacts with vesicle-tethering factors at the Golgi apparatus.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
0 genes with posterior transmembrane prediction > 50%