FOG15231
EOG8CFXRT

sce:TDA6;VPS62

Genes: 32

SGD Description
Putative protein of unknown function; induced by treatment with 8-methoxypsoralen and UVA irradiation; null mutant is sensitive to expression of the top1-T722A allele; TDA6 has a paralog, VPS62, that arose from the whole genome duplication|Vacuolar protein sorting (VPS) protein; required for cytoplasm to vacuole targeting of proteins; VPS62 has a paralog, TDA6, that arose from the whole genome duplication


AspGD Description
Ortholog of A. nidulans FGSC A4 : AN4807, A. oryzae RIB40 : AO090020000293, Aspergillus wentii : Aspwe1_0052428, Aspergillus sydowii : Aspsy1_0087808 and Aspergillus terreus NIH2624 : ATET_08721|Ortholog of S. cerevisiae : TDA6, A. nidulans FGSC A4 : AN7454, A. fumigatus Af293 : Afu2g05980, A. oryzae RIB40 : AO090001000716 and Aspergillus wentii : Aspwe1_0055229


References

Bonangelino CJ, et al. (2002 Jul). Genomic screen for vacuolar protein sorting genes in Saccharomyces cerevisiae.

Malavazi I, et al. (2007 Oct). Transcriptome analysis of the Aspergillus nidulans AtmA (ATM, Ataxia-Telangiectasia mutated) null mutant.

Dardalhon M, et al. (2007 Sep). Specific transcriptional responses induced by 8-methoxypsoralen and UVA in yeast.

Reid RJ, et al. (2011 Mar). Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
8 genes with posterior transmembrane prediction > 50%