FOG15219
EOG8CFXTD

sce:absent

Genes: 32

SGD Description
NADHX dehydratase; converts (S)-NADHX to NADH in an ATP-dependent manner; homologous to Carkd in mammals, and the C-terminal domain of YjeF in E.coli; enzyme is widespread in eukaryotes, prokaryotes and archaea; YKL151C promoter contains STREs (stress response elements) and expression is induced by heat shock or methyl methanesulfonate; green fluorescent protein (GFP)-fusion protein localizes to the cytoplasm; protein abundance increases in response to DNA replication stress


PomBase Description
NADHX dehydratase (predicted)


AspGD Description
Ortholog(s) have ATP-dependent NAD(P)H-hydrate dehydratase activity, role in nicotinamide nucleotide metabolic process and cytosol localization


References

MEINHART JO, et al. (1956 Jun). Enzymatic conversion of a reduced diphosphopyridine nucleotide derivative to reduced diphosphopyridine nucleotide.

Acheson SA, et al. (1988 Sep 20). Equilibrium of 5,6-hydration of NADH and mechanism of ATP-dependent dehydration.

Marbaix AY, et al. (2011 Dec 2). Extremely conserved ATP- or ADP-dependent enzymatic system for nicotinamide nucleotide repair.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%