FOG15202
EOG8CJSXZ

sce:SPT6

Genes: 33

SGD Description
Nucleosome remodeling protein; functions in various aspects of transcription, chromatin maintenance, and RNA processing; required for the maintenance of chromatin structure during transcription in order to inhibit transcription from promoters within the coding region; required for H3K36 trimethylation but not dimethylation by Set2p


PomBase Description
nucleosome remodeling protein Spt6


AspGD Description
Has domain(s) with predicted hydrolase activity, acting on ester bonds activity and role in nucleobase-containing compound metabolic process


References

Swanson MS, et al. (1990 Sep). SPT6, an essential gene that affects transcription in Saccharomyces cerevisiae, encodes a nuclear protein with an extremely acidic amino terminus.

Maclennan AJ, et al. (1993 Dec). A yeast SH2 domain.

Hartzog GA, et al. (1998 Feb 1). Evidence that Spt4, Spt5, and Spt6 control transcription elongation by RNA polymerase II in Saccharomyces cerevisiae.

Kaplan CD, et al. (2003 Aug 22). Transcription elongation factors repress transcription initiation from cryptic sites.

Chibana H, et al. (2005 Aug). Sequence finishing and gene mapping for Candida albicans chromosome 7 and syntenic analysis against the Saccharomyces cerevisiae genome.

Kaplan CD, et al. (2005 Jan 14). Interaction between transcription elongation factors and mRNA 3'-end formation at the Saccharomyces cerevisiae GAL10-GAL7 locus.

Adkins MW, et al. (2006 Feb 3). Transcriptional activators are dispensable for transcription in the absence of Spt6-mediated chromatin reassembly of promoter regions.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%