FOG15133
EOG8CNP8V

sce:MGM101

Genes: 31

SGD Description
Protein with a role in mitochondrial DNA recombinational repair; also involved in interstrand cross-link repair; binds to and catalyzes the annealing of single-stranded mtDNA; oligomerizes to form rings and filaments; related to Rad52-type recombination proteins, with limited overall similarity but sharing conserved functionally important residues; component of the mitochondrial nucleoid, required for the repair of oxidative mtDNA damage and mitochondrial genome maintenance


PomBase Description
mitochondrial DNA repair protein (predicted)


AspGD Description
Ortholog(s) have single-stranded DNA binding activity and role in DNA strand renaturation, cellular response to drug, interstrand cross-link repair, mitochondrial genome maintenance, recombinational repair


References

Chen XJ, et al. (1993 Jul 25). MGM101, a nuclear gene involved in maintenance of the mitochondrial genome in Saccharomyces cerevisiae.

Clark-Walker GD, et al. (1996 Oct 28). A vital function for mitochondrial DNA in the petite-negative yeast Kluyveromyces lactis.

Meeusen S, et al. (1999 Apr 19). Mgm101p is a novel component of the mitochondrial nucleoid that binds DNA and is required for the repair of oxidatively damaged mitochondrial DNA.

Sickmann A, et al. (2003 Nov 11). The proteome of Saccharomyces cerevisiae mitochondria.

Wilson-Grady JT, et al. (2008 Mar). Phosphoproteome analysis of fission yeast.

Wendland J, et al. (2011 Dec). Genome evolution in the eremothecium clade of the Saccharomyces complex revealed by comparative genomics.

Rhind N, et al. (2011 May 20). Comparative functional genomics of the fission yeasts.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

McDonald KR, et al. (2016 Sep). Pfh1 Is an Accessory Replicative Helicase that Interacts with the Replisome to Facilitate Fork Progression and Preserve Genome Integrity.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%