FOG15116
EOG8CRJDZ

sce:CFT1

Genes: 33

SGD Description
RNA-binding subunit of the mRNA cleavage and polyadenylation factor; involved in poly(A) site recognition and required for both pre-mRNA cleavage and polyadenylation, 51% sequence similarity with mammalian AAUAA-binding subunit of CPSF


PomBase Description
cleavage factor one Cft1 (predicted)


AspGD Description
Ortholog(s) have cytosol, mRNA cleavage and polyadenylation specificity factor complex localization


References

Stumpf G, et al. (1996 Nov 29). Dependence of yeast pre-mRNA 3'-end processing on CFT1: a sequence homolog of the mammalian AAUAAA binding factor.

Dichtl B, et al. (2002 Aug 1). Yhh1p/Cft1p directly links poly(A) site recognition and RNA polymerase II transcription termination.

Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 6 genes with posterior transmembrane prediction > 50%