FOG15023
EOG8CZ921

sce:ERG28

Genes: 32

SGD Description
Endoplasmic reticulum membrane protein; may facilitate protein-protein interactions between the Erg26p dehydrogenase and the Erg27p 3-ketoreductase and/or tether these enzymes to the ER, also interacts with Erg6p


PomBase Description
Erg28 protein (predicted)


AspGD Description
Protein similar to lipid metabolism protein Erg28p; expression repressed by tunicamycin and DTT


References

Gachotte D, et al. (2001 Jan). A novel gene conserved from yeast to humans is involved in sterol biosynthesis.

Mo C, et al. (2002 Jul 23). Protein-protein interactions among C-4 demethylation enzymes involved in yeast sterol biosynthesis.

Mo C, et al. (2004 Nov 8). The ERG28-encoded protein, Erg28p, interacts with both the sterol C-4 demethylation enzyme complex as well as the late biosynthetic protein, the C-24 sterol methyltransferase (Erg6p).

Mo C, et al. (2005 Sep). Erg28p is a key protein in the yeast sterol biosynthetic enzyme complex.

Kim H, et al. (2006 Jul 25). A global topology map of the Saccharomyces cerevisiae membrane proteome.

Savoldi M, et al. (2008 Oct). Farnesol induces the transcriptional accumulation of the Aspergillus nidulans Apoptosis-Inducing Factor (AIF)-like mitochondrial oxidoreductase.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 32 genes with posterior transmembrane prediction > 50%