FOG14983
EOG8D258Z

sce:YTH1

Genes: 34

SGD Description
Essential RNA-binding component of cleavage and polyadenylation factor; contains five zinc fingers; required for pre-mRNA 3'-end processing and polyadenylation; relocalizes to the cytosol in response to hypoxia


PomBase Description
mRNA cleavage and polyadenylation specificity factor complex Yth1


AspGD Description
Ortholog(s) have RNA binding activity, role in mRNA polyadenylation, pre-mRNA cleavage required for polyadenylation, response to drug and cytosol, mRNA cleavage and polyadenylation specificity factor complex localization


References

Barabino SM, et al. (1997 Jul 1). The 30-kD subunit of mammalian cleavage and polyadenylation specificity factor and its yeast homolog are RNA-binding zinc finger proteins.

Barabino SM, et al. (2000 Jul 17). Distinct roles of two Yth1p domains in 3'-end cleavage and polyadenylation of yeast pre-mRNAs.

Helmling S, et al. (2001 Mar). Fip1 regulates the activity of Poly(A) polymerase through multiple interactions.

Nedea E, et al. (2003 Aug 29). Organization and function of APT, a subcomplex of the yeast cleavage and polyadenylation factor involved in the formation of mRNA and small nucleolar RNA 3'-ends.

Tacahashi Y, et al. (2003 Mar 15). Functional dissection of the zinc finger and flanking domains of the Yth1 cleavage/polyadenylation factor.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%