FOG14944
EOG8D51GD

sce:STE4

Genes: 33

SGD Description
G protein beta subunit; forms a dimer with Ste18p to activate the mating signaling pathway, forms a heterotrimer with Gpa1p and Ste18p to dampen signaling; may recruit Rho1p to the polarized growth site during mating; contains WD40 repeats


PomBase Description
heterotrimeric G protein beta subunit Git5


AspGD Description
G-protein beta subunit; expressed in germinating conidia


References

Whiteway M, et al. (1989 Feb 10). The STE4 and STE18 genes of yeast encode potential beta and gamma subunits of the mating factor receptor-coupled G protein.

Spain BH, et al. (1995 Oct 27). Truncated forms of a novel yeast protein suppress the lethality of a G protein alpha subunit deficiency by interacting with the beta subunit.

Adams TH, et al. (1998 Dec). Coordinate control of secondary metabolite production and asexual sporulation in Aspergillus nidulans.

Yu JH, et al. (1999 Jan). Extragenic suppressors of loss-of-function mutations in the aspergillus FlbA regulator of G-protein signaling domain protein.

Rosén S, et al. (1999 Oct 15). The Aspergillus nidulans sfaD gene encodes a G protein beta subunit that is required for normal growth and repression of sporulation.

Coca MA, et al. (2000 Apr). Heterotrimeric G-proteins of a filamentous fungus regulate cell wall composition and susceptibility to a plant PR-5 protein.

Flanary PL, et al. (2000 Jun 16). Functional analysis of Plp1 and Plp2, two homologues of phosducin in yeast.

Han KH, et al. (2001 Jul). The nsdD gene encodes a putative GATA-type transcription factor necessary for sexual development of Aspergillus nidulans.

Muthuvijayan V, et al. (2004). In silico reconstruction of nutrient-sensing signal transduction pathways in Aspergillus nidulans.

Bok JW, et al. (2004 Apr). LaeA, a regulator of secondary metabolism in Aspergillus spp.

Fedorova ND, et al. (2005 Dec 8). Comparative analysis of programmed cell death pathways in filamentous fungi.

Choi CJ, et al. (2005 Jul). Isolation and characterization of the Aspergillus nidulans eglC gene encoding a putative beta-1,3-endoglucanase.

Lafon A, et al. (2005 Sep). The heterotrimeric G-protein GanB(alpha)-SfaD(beta)-GpgA(gamma) is a carbon source sensor involved in early cAMP-dependent germination in Aspergillus nidulans.

Seo JA, et al. (2005 Sep). Multiple roles of a heterotrimeric G-protein gamma-subunit in governing growth and development of Aspergillus nidulans.

Yu JH, et al. (2006 Apr). Heterotrimeric G protein signaling and RGSs in Aspergillus nidulans.

Seo JA, et al. (2006 Feb). The phosducin-like protein PhnA is required for Gbetagamma-mediated signaling for vegetative growth, developmental control, and toxin biosynthesis in Aspergillus nidulans.

Lafon A, et al. (2006 Jul). G-protein and cAMP-mediated signaling in aspergilli: a genomic perspective.

Paoletti M, et al. (2007 Aug 21). Mating type and the genetic basis of self-fertility in the model fungus Aspergillus nidulans.

Emri T, et al. (2008 Jun). Heterotrimeric G protein mediated regulation of proteinase production in Aspergillus nidulans.

Han KH, et al. (2008 Mar). The Aspergillus nidulans esdC (early sexual development) gene is necessary for sexual development and is controlled by veA and a heterotrimeric G protein.

Soriani FM, et al. (2008 Mar). Functional characterization of the Aspergillus fumigatus CRZ1 homologue, CrzA.

Harris SD, et al. (2009 Mar). Morphology and development in Aspergillus nidulans: a complex puzzle.

Szilágyi M, et al. (2011 Dec). Extracellular proteinase formation in carbon starving Aspergillus nidulans cultures--physiological function and regulation.

Park HS, et al. (2012 Dec). Genetic control of asexual sporulation in filamentous fungi.

Bayram O, et al. (2012 Jan). Coordination of secondary metabolism and development in fungi: the velvet family of regulatory proteins.

Dyer PS, et al. (2012 Jan). Sexual development and cryptic sexuality in fungi: insights from Aspergillus species.

Kong Q, et al. (2013). Gβ-like CpcB plays a crucial role for growth and development of Aspergillus nidulans and Aspergillus fumigatus.

Krijgsheld P, et al. (2013 Mar 15). Development in Aspergillus.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%