FOG14827
EOG8DFN7J
sce:CUP9
Genes: 5
SGD DescriptionHomeodomain-containing transcriptional repressor; regulates expression of PTR2, which encodes a major peptide transporter; imported peptides activate ubiquitin-dependent proteolysis, resulting in degradation of Cup9p and de-repression of PTR2 transcription; CUP9 has a paralog, TOS8, that arose from the whole genome duplication; protein abundance increases in response to DNA replication stress
References
Knight SA, et al. (1994 Dec). Identification and analysis of a Saccharomyces cerevisiae copper homeostasis gene encoding a homeodomain protein.
Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.