FOG14805
EOG8DJHC7

sce:ROK1

Genes: 33

SGD Description
RNA-dependent ATPase; involved in pre-rRNA processing at sites A0, A1, and A2, and in control of cell cycle progression; contains two upstream open reading frames (uORFs) in 5' untranslated region which regulate translation


PomBase Description
ATP-dependent RNA helicase Rok1 (predicted)


AspGD Description
Ortholog(s) have cytosol localization


References

Song Y, et al. (1995 Dec 1). ROK1, a high-copy-number plasmid suppressor of kem1, encodes a putative ATP-dependent RNA helicase in Saccharomyces cerevisiae.

Venema J, et al. (1997 Jun). Rok1p is a putative RNA helicase required for rRNA processing.

Torchet C, et al. (1998 Dec). Two mutant forms of the S1/TPR-containing protein Rrp5p affect the 18S rRNA synthesis in Saccharomyces cerevisiae.

Oh JY, et al. (1999 Jul 1). ATP hydrolysis activity of the DEAD box protein Rok1p is required for in vivo ROK1 function.

Kim WI, et al. (2000 Mar 30). Identification of a putative DEAD-box RNA helicase and a zinc-finger protein in Candida albicans by functional complementation of the S. cerevisiae rok1 mutation.

Park YU, et al. (2002 May 3). Two-hybrid cloning and characterization of OSH3, a yeast oxysterol-binding protein homolog.

Schäfer T, et al. (2003 Mar 17). The path from nucleolar 90S to cytoplasmic 40S pre-ribosomes.

Vos HR, et al. (2004). U3 snoRNP and Rrp5p associate independently with Saccharomyces cerevisiae 35S pre-rRNA, but Rrp5p is essential for association of Rok1p.

Yano T, et al. (2004 Feb 27). Deletion of OSH3 gene confers resistance against ISP-1 in Saccharomyces cerevisiae.

Kim J, et al. (2004 Sep 3). Posttranscriptional regulation of the karyogamy gene by Kem1p/Xrn1p exoribonuclease and Rok1p RNA helicase of Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%