FOG14797
EOG8DJHDC

sce:SEC13

Genes: 30

SGD Description
Structural component of 3 distinct complexes; subunit of Nup84 nuclear pore sub-complex (NPC), COPII vesicle coat, and Seh1-associated (SEA) complex; COPII vesicle coat is required for ER to Golgi transport; the Nup84 subcomplex contributes to nucleocytoplasmic transport, NPC biogenesis and processes that may require localization of chromosomes at the nuclear periphery, including transcription; homologous to human SEC13; abundance increases under DNA replication stress


PomBase Description
COPII-coated vesicle component Sec13


AspGD Description
COPII complex subunit; expression enhanced by maltose


References

Novick P, et al. (1980 Aug). Identification of 23 complementation groups required for post-translational events in the yeast secretory pathway.

Novick P, et al. (1981 Aug). Order of events in the yeast secretory pathway.

Kaiser CA, et al. (1990 May 18). Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathway.

Pryer NK, et al. (1993 Feb). Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

Bednarek SY, et al. (1995 Dec 29). COPI- and COPII-coated vesicles bud directly from the endoplasmic reticulum in yeast.

Siniossoglou S, et al. (1996 Jan 26). A novel complex of nucleoporins, which includes Sec13p and a Sec13p homolog, is essential for normal nuclear pores.

Kuehn MJ, et al. (1996 Nov). Amino acid permeases require COPII components and the ER resident membrane protein Shr3p for packaging into transport vesicles in vitro.

Roberg KJ, et al. (1997 Dec). Control of amino acid permease sorting in the late secretory pathway of Saccharomyces cerevisiae by SEC13, LST4, LST7 and LST8.

Salama NR, et al. (1997 Feb). Sec31 encodes an essential component of the COPII coat required for transport vesicle budding from the endoplasmic reticulum.

Campbell JL, et al. (1997 Feb 4). Selective packaging of cargo molecules into endoplasmic reticulum-derived COPII vesicles.

Roberg KJ, et al. (1997 Jun 30). Physiological regulation of membrane protein sorting late in the secretory pathway of Saccharomyces cerevisiae.

Sütterlin C, et al. (1997 Nov). Specific requirements for the ER to Golgi transport of GPI-anchored proteins in yeast.

Shaywitz DA, et al. (1997 Oct 10). COPII subunit interactions in the assembly of the vesicle coat.

Matsuoka K, et al. (1998 Apr 17). COPII-coated vesicle formation reconstituted with purified coat proteins and chemically defined liposomes.

Gilstring CF, et al. (1999 Nov). Shr3p mediates specific COPII coatomer-cargo interactions required for the packaging of amino acid permeases into ER-derived transport vesicles.

Matsuoka K, et al. (2000 Apr). The use of liposomes to study COPII- and COPI-coated vesicle formation and membrane protein sorting.

Siniossoglou S, et al. (2000 Apr 3). Structure and assembly of the Nup84p complex.

Rout MP, et al. (2000 Feb 21). The yeast nuclear pore complex: composition, architecture, and transport mechanism.

Antonny B, et al. (2001 Jun). Dynamics of the COPII coat with GTP and stable analogues.

Belden WJ, et al. (2001 Nov 16). Distinct roles for the cytoplasmic tail sequences of Emp24p and Erv25p in transport between the endoplasmic reticulum and Golgi complex.

Matsuoka K, et al. (2001 Nov 20). Surface structure of the COPII-coated vesicle.

Lederkremer GZ, et al. (2001 Sep 11). Structure of the Sec23p/24p and Sec13p/31p complexes of COPII.

Fatal N, et al. (2002 Dec). Selective protein exit from yeast endoplasmic reticulum in absence of functional COPII coat component Sec13p.

Lutzmann M, et al. (2002 Feb 1). Modular self-assembly of a Y-shaped multiprotein complex from seven nucleoporins.

Supek F, et al. (2002 Sep 16). Sec16p potentiates the action of COPII proteins to bud transport vesicles.

Ryan KJ, et al. (2002 Sep 5). Isolation and characterization of new Saccharomyces cerevisiae mutants perturbed in nuclear pore complex assembly.

Antonny B, et al. (2003 Apr). Self-assembly of minimal COPII cages.

Barlowe C, et al. (2003 Jun). Signals for COPII-dependent export from the ER: what's the ticket out?

Suntharalingam M, et al. (2003 Jun). Peering through the pore: nuclear pore complex structure, assembly, and function.

van Vliet C, et al. (2003 Sep). Intracellular sorting and transport of proteins.

Sato K, et al. (2004 Jan 9). Reconstitution of coat protein complex II (COPII) vesicle formation from cargo-reconstituted proteoliposomes reveals the potential role of GTP hydrolysis by Sar1p in protein sorting.

Fernández-Arenas E, et al. (2004 Oct). Low virulent strains of Candida albicans: unravelling the antigens for a future vaccine.

Sims AH, et al. (2005 May). Transcriptome analysis of recombinant protein secretion by Aspergillus nidulans and the unfolded-protein response in vivo.

Osmani AH, et al. (2006 Dec). Systematic deletion and mitotic localization of the nuclear pore complex proteins of Aspergillus nidulans.

Dokudovskaya S, et al. (2011 Jun). A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.

Van Damme P, et al. (2012 Jul 31). N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%