FOG14729
EOG8DR7VB

sce:TRM12

Genes: 24

SGD Description
S-adenosylmethionine-dependent methyltransferase; required for wybutosine formation in phenylalanine-accepting tRNA; member of the seven beta-strand family


PomBase Description
tRNA methyltransferase Trm12 (predicted)


AspGD Description
Ortholog(s) have S-adenosylmethionine-dependent methyltransferase activity, transferase activity, transferring alkyl or aryl (other than methyl) groups activity and role in tRNA methylation, wybutosine biosynthetic process


References

Kalhor HR, et al. (2005 Aug 26). A novel methyltransferase required for the formation of the hypermodified nucleoside wybutosine in eucaryotic tRNA.

Noma A, et al. (2006). Ribonucleome analysis identified enzyme genes responsible for wybutosine synthesis.

Noma A, et al. (2006 May 17). Biosynthesis of wybutosine, a hyper-modified nucleoside in eukaryotic phenylalanine tRNA.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%