FOG14679
EOG8DV435

sce:RAD7

Genes: 34

SGD Description
Nucleotide excision repair (NER) protein; binds damaged DNA during NER; binds DNA in an ATP-dependent manner (with Rad16p) during NER; required for repair of non-transcribed chromatin; subunit of Nucleotide Excision Repair Factor 4 (NEF4) and the Elongin-Cullin-Socs (ECS) ligase complex


PomBase Description
Rad7 homolog Rhp7


AspGD Description
Ortholog(s) have role in nucleotide-excision repair and mitotic spindle pole body, nucleotide-excision repair complex localization


References

Nasim A, et al. (1975 Apr). Genetic control of radiation sensitivity in Schizosaccharomyces pombe.

Perozzi G, et al. (1986 May). RAD7 gene of Saccharomyces cerevisiae: transcripts, nucleotide sequence analysis, and functional relationship between the RAD7 and RAD23 gene products.

Huang ME, et al. (1994 Jun). Revised nucleotide sequence of the COR region of yeast Saccharomyces cerevisiae chromosome X.

Perego P, et al. (1998 Jul). Sensitivity to cisplatin and platinum-containing compounds of Schizosaccharomyces pombe rad mutants.

Reed SH, et al. (1999 Dec 1). Yeast autonomously replicating sequence binding factor is involved in nucleotide excision repair.

Lombaerts M, et al. (1999 Sep 1). Characterization of the rhp7(+) and rhp16(+) genes in Schizosaccharomyces pombe.

Marti TM, et al. (2003 Jun). Repair of damaged and mismatched DNA by the XPC homologues Rhp41 and Rhp42 of fission yeast.

Yu S, et al. (2004 Mar 4). The yeast Rad7/Rad16/Abf1 complex generates superhelical torsion in DNA that is required for nucleotide excision repair.

Deshpande GP, et al. (2009 May 1). Screening a genome-wide S. pombe deletion library identifies novel genes and pathways involved in genome stability maintenance.

Stewart EV, et al. (2011 Apr 22). Yeast SREBP cleavage activation requires the Golgi Dsc E3 ligase complex.

Pancaldi V, et al. (2012 Apr). Predicting the fission yeast protein interaction network.

Latypov VF, et al. (2012 Jul 13). Atl1 regulates choice between global genome and transcription-coupled repair of O(6)-alkylguanines.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Dudin O, et al. (2017 Apr). A systematic screen for morphological abnormalities during fission yeast sexual reproduction identifies a mechanism of actin aster formation for cell fusion.

Guydosh NR, et al. (2017 Sep 25). Regulated Ire1-dependent mRNA decay requires no-go mRNA degradation to maintain endoplasmic reticulum homeostasis in <i>S. pombe</i>.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%