FOG14567
EOG8F4QW6

sce:absent

Genes: 12

PomBase Description
histone lysine H3-K20 methyltransferase Set9


AspGD Description
Ortholog(s) have histone methyltransferase activity (H4-K20 specific), nucleosome binding activity and role in cellular protein localization, chromatin silencing, histone H4-K20 methylation, mitotic DNA damage checkpoint


References

Sanders SL, et al. (2004 Nov 24). Methylation of histone H4 lysine 20 controls recruitment of Crb2 to sites of DNA damage.

Du LL, et al. (2006 Jun 15). Histone modification-dependent and -independent pathways for recruitment of checkpoint protein Crb2 to double-strand breaks.

Lan F, et al. (2007 Apr 13). S. pombe LSD1 homologs regulate heterochromatin propagation and euchromatic gene transcription.

Dixon SJ, et al. (2008 Oct 28). Significant conservation of synthetic lethal genetic interaction networks between distantly related eukaryotes.

Wang Y, et al. (2009 Feb 27). Regulation of Set9-mediated H4K20 methylation by a PWWP domain protein.

Holmes A, et al. (2012 Dec 27). Lsd1 and lsd2 control programmed replication fork pauses and imprinting in fission yeast.

Wei Y, et al. (2014). Mdb1, a fission yeast homolog of human MDC1, modulates DNA damage response and mitotic spindle function.

Sideri T, et al. (2014 Dec 1). Parallel profiling of fission yeast deletion mutants for proliferation and for lifespan during long-term quiescence.

Guo Y, et al. (2014 Jul). Large scale screening of genetic interaction with sgf73(+) in fission yeast.

Mejia-Ramirez E, et al. (2015 Sep). Critical Function of γH2A in S-Phase.

Zeng M, et al. (2016 Apr 21). CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent resection.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 0 genes with posterior transmembrane prediction > 50%