FOG14422
EOG8FJ6RK

sce:MGS1

Genes: 35

SGD Description
Protein with DNA-dependent ATPase and ssDNA annealing activities; involved in maintenance of genome; interacts functionally with DNA polymerase delta; homolog of human Werner helicase interacting protein (WHIP); forms nuclear foci upon DNA replication stress


PomBase Description
DNA replication ATPase (predicted)


AspGD Description
Has domain(s) with predicted ATP binding, nucleoside-triphosphatase activity, nucleotide binding activity|Has domain(s) with predicted four-way junction helicase activity, nucleoside-triphosphatase activity, nucleotide binding activity and role in DNA recombination, DNA repair


References

Guiard B, et al. (1976). Complete amino acid sequence of the heme-binding core in bakers' yeast cytochrome b2 (L-(+)-lactate dehydrogenase).

Hishida T, et al. (2001 Jul 17). A yeast gene, MGS1, encoding a DNA-dependent AAA(+) ATPase is required to maintain genome stability.

Kawabe Yi, et al. (2001 Jun 8). A novel protein interacts with the Werner's syndrome gene product physically and functionally.

Branzei D, et al. (2002 Nov). The product of Saccharomyces cerevisiae WHIP/MGS1, a gene related to replication factor C genes, interacts functionally with DNA polymerase delta.

Mitochondrial localization predictions
Predotar TargetP MitoProt
Raw data
Phobius transmembrane predictions
1 genes with posterior transmembrane prediction > 50%