FOG14401
EOG8FJ6V7

sce:RRP40

Genes: 34

SGD Description
Exosome non-catalytic core component; involved in 3'-5' RNA processing and degradation in both the nucleus and the cytoplasm; predicted to contain both S1 and KH RNA binding domains; has similarity to human hRrp40p (EXOSC3)


PomBase Description
exosome subunit Rrp40


AspGD Description
Has domain(s) with predicted RNA binding activity and exosome (RNase complex) localization


References

Allmang C, et al. (1999 Aug 15). The yeast exosome and human PM-Scl are related complexes of 3' --> 5' exonucleases.

Liu Q, et al. (2006 Dec 15). Reconstitution, activities, and structure of the eukaryotic RNA exosome.

Dziembowski A, et al. (2007 Jan). A single subunit, Dis3, is essentially responsible for yeast exosome core activity.

Schaeffer D, et al. (2009 Jan). The exosome contains domains with specific endoribonuclease, exoribonuclease and cytoplasmic mRNA decay activities.

Coy S, et al. (2013). The Sm complex is required for the processing of non-coding RNAs by the exosome.

Malecki M, et al. (2013 Jul 3). The exoribonuclease Dis3L2 defines a novel eukaryotic RNA degradation pathway.

Carpy A, et al. (2014 Aug). Absolute proteome and phosphoproteome dynamics during the cell cycle of Schizosaccharomyces pombe (Fission Yeast).

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 1 genes with posterior transmembrane prediction > 50%