FOG14349
EOG8FQZ6Z

sce:NPR3

Genes: 31

SGD Description
Subunit of SEA (Seh1-associated), Npr2/3, and Iml1p complexes; Npr2/3 complex mediates downregulation of TORC1 activity upon amino acid limitation; SEA complex is a coatomer-related complex that associates dynamically with the vacuole; Iml1p complex (Iml1p-Npr2p-Npr3p) is required for non-nitrogen-starvation (NNS)-induced autophagy; required for Npr2p phosphorylation and Iml1p-Npr2p interaction; null mutant shows delayed meiotic DNA replication and double-strand break repair


PomBase Description
SEA/Iml1/Npr2/3 complex subunit Npr3 (predicted)


AspGD Description
Ortholog(s) have role in cellular response to amino acid starvation, meiotic nuclear division, negative regulation of Ras protein signal transduction and negative regulation of TOR signaling, more


References

Enyenihi AH, et al. (2003 Jan). Large-scale functional genomic analysis of sporulation and meiosis in Saccharomyces cerevisiae.

Gruhler A, et al. (2005 Mar). Quantitative phosphoproteomics applied to the yeast pheromone signaling pathway.

Chi A, et al. (2007 Feb 13). Analysis of phosphorylation sites on proteins from Saccharomyces cerevisiae by electron transfer dissociation (ETD) mass spectrometry.

Neklesa TK, et al. (2009 Jun). A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.

Dokudovskaya S, et al. (2011 Jun). A conserved coatomer-related complex containing Sec13 and Seh1 dynamically associates with the vacuole in Saccharomyces cerevisiae.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 17 genes with posterior transmembrane prediction > 50%