FOG14152
EOG8G79HH

sce:PNT1

Genes: 5

SGD Description
Mitochondrial integral inner membrane protein; involved in membrane insertion of C-terminus of Cox2p, interacts genetically and physically with Cox18p; deletion mutant sensitive to the anti-Pneumocystis carinii drug pentamidine


References

Ludewig G, et al. (1994 Dec). Characterization of the PNT1 pentamidine resistance gene of Saccharomyces cerevisiae.

Archer JE, et al. (1995 Aug 11). Rbl2p, a yeast protein that binds to beta-tubulin and participates in microtubule function in vivo.

He S, et al. (1999 Oct). Mutations affecting a yeast mitochondrial inner membrane protein, pnt1p, block export of a mitochondrially synthesized fusion protein from the matrix.

Saracco SA, et al. (2002 Apr). Cox18p is required for export of the mitochondrially encoded Saccharomyces cerevisiae Cox2p C-tail and interacts with Pnt1p and Mss2p in the inner membrane.

Mitochondrial localization predictions
Predotar	TargetP	MitoProt
Raw data
Phobius transmembrane predictions 5 genes with posterior transmembrane prediction > 50%